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Epipremnum Amplissima will adapt and live in most lighting conditions. Optimal lighting conditions are moderate indirect light. Careful not to have it in bright direct sun as this will scorch the leaves.
Water your Epipremnum Amplissima thoroughly when the soil is almost dry. Overwatering is the number one killer of Epipremnum. Signs of overwatering are pale yellow leaves on new and old leaves. An underwatered plant may appear wilted.
This is a low-maintenance plant that should be happy with average household conditions. You can fertilize every month or so during spring through summer with a normal house plant fertilizer. It would love to grow up a moss pole rather than trailing. The cuttings are easily propagated in either water or directly into the soil. Wiping down the leaves once in a while will keep the dust off and have the plant looking nice and tidy.